Research

Macro partitioning

High intake of total dietary fats, saturated fatty acids (SFA), monounsaturated fatty acids (MUFA), and polyunsaturated fatty acids (PUFA) is not significantly associated with the incidence risk of cardiovascular disease (CVD).

Current guidelines often recommend limiting total fat and saturated fat intake to prevent heart disease. However, this large, long-term study found no significant link between the amount of total fat, saturated fat, or unsaturated fats consumed and the risk of developing cardiovascular disease. This suggests that strictly limiting fat intake may not be necessary for CVD prevention, and attention might be better placed on the quality of fats and the overall dietary pattern.

GoodRefutesHIGH confidence
Total fat, animal and plant sources of fats were not associated with risk of CVD events. No significant associations were found between total SFA, lauric acid, myristic acid, stearic acid, palmitic acid as well as MUFA and PUFA and CVD incidence.
Zahra Gaeini et al. · Nutrition & Metabolism · 2021

Why this rating

Large prospective cohort study (n=2809) with long follow-up (median 10.6 years) and rigorous adjustment for confounders.

Source

The association between dietary fats and the incidence risk of cardiovascular outcomes: Tehran Lipid and Glucose Study

Zahra Gaeini et al. · Nutrition & Metabolism · 2021

cohort · n=2809Cited 10×
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