Research

Macro partitioning

Whey protein supplementation (concentrated, hydrolyzed, or isolated) significantly reduces fat mass compared to isocaloric carbohydrate placebos in healthy adults undergoing resistance training, but does not significantly increase fat-free mass.

If you are doing resistance training, switching from a carbohydrate-based post-workout drink to whey protein may help you lose a small amount of fat mass over ~2 months. Do not expect this to build muscle mass; the study found no significant difference in fat-free mass gains between whey and placebo groups.

ModerateQualifiesMEDIUM confidence
The weighted mean difference (WMD) was statistically significant for FM loss (WMD = −0.96, 95% CI = −1.37, −0.55, p < 0.001)... There was no significant effect on FFM in any of the scenarios investigated (p > 0.05).
Luis Henrique Almeida Castro et al. · Nutrients · 2019

Why this rating

Meta-analysis of RCTs, but the authors note 'low methodological quality' and 'low risk of bias' in only one study.

Source

Comparative Meta-Analysis of the Effect of Concentrated, Hydrolyzed, and Isolated Whey Protein Supplementation on Body Composition of Physical Activity Practitioners

Luis Henrique Almeida Castro et al. · Nutrients · 2019

DOI 10.3390/nu11092047

Meta-analysis · 8 studiesCited 26×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →