Research

Macro partitioning

Isocaloric replacement of 3% energy from low-quality carbohydrates or saturated fat with plant protein is associated with significantly lower total, cardiovascular, and cancer mortality.

Replace 3% of your daily energy intake from refined carbohydrates and saturated fats with plant protein sources like beans, lentils, nuts, and whole grains. This simple substitution is associated with a 10% lower risk of death from all causes.

GoodSupportsHIGH confidence
Notably, isocalorically replacing 3% energy from low-quality carbohydrates with plant protein was associated with 10% (HR: 0.90; 95% CI: 0.89, 0.91), 11% (HR: 0.89; 95% CI: 0.86, 0.91), and 4% (HR: 0.96; 95% CI: 0.94, 0.98) lower risks of mortality from all causes, all CVDs, and all cancers, respectively.
Yimin Zhao et al. · Journal of Internal Medicine · 2023

Why this rating

Large prospective cohort, long follow-up, but observational design.

Source

Low‐carbohydrate diets, low‐fat diets, and mortality in middle‐aged and older people: A prospective cohort study

Yimin Zhao et al. · Journal of Internal Medicine · 2023

cohort · n=371159Cited 25×
Read the paper

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