Hormonal
A low-glycemic index (GI) diet is non-inferior to a whole-grain wheat-fiber diet in preventing arterial wall damage (measured by carotid vessel wall volume) over 3 years in patients with type 2 diabetes.
For people with type 2 diabetes, choosing a low-GI diet (emphasizing lentils, beans, and specific whole grains) is just as effective as a high-wheat-fiber diet for protecting arterial walls over the long term. While the wheat-fiber diet showed a significant increase in arterial wall volume in this study, the low-GI diet did not, suggesting it is a viable and effective strategy for cardiovascular risk reduction.
No treatment differences were seen in VWV... noninferiority of the low-GI diet compared with the wheat-fiber diet was demonstrated... indicating that the low-GI diet was not inferior therapeutically to the whole wheat diet.
Why this rating
Randomized Controlled Trial, 3-year duration, MRI-measured primary outcome, but low adherence to ideal diet targets.
Source
Glycemic Index Versus Wheat Fiber on Arterial Wall Damage in Diabetes: A Randomized Controlled Trial
David J.A. Jenkins et al. · Diabetes Care · 2022
DOI 10.2337/dc22-1028
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