Macro partitioning
Co-ingesting a mixture of three microbial proteases (OPTIZIOME P3) with 25g of pea protein isolate significantly increases early postprandial plasma amino acid availability (0-2h) compared to pea protein alone in healthy adults.
If you are using pea protein, adding a specific microbial protease supplement (like OPTIZIOME P3) with your shake will help your body absorb amino acids faster in the first two hours after drinking it. This is particularly useful around workouts when you want a quick nutrient spike. The study used one capsule (31,875 HUT units) mixed with 25g of pea protein and 300ml of water. It was safe and did not cause stomach issues.
Microbial protease co-ingestion increases plasma TAA concentrations (0–5 h) and leucine, BCAA, EAA, and TAA availability in the early postprandial period (0‒2 h) compared with ingesting pea protein with placebo in healthy adults.
Why this rating
Randomized, double-blind, placebo-controlled crossover trial with a sufficient sample size (n=24) and rigorous statistical analysis, though limited to acute effects in healthy young adults.
Source
Acute Microbial Protease Supplementation Increases Net Postprandial Plasma Amino Acid Concentrations After Pea Protein Ingestion in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
Kevin J.M. Paulussen et al. · Journal of Nutrition · 2024
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