Research
Hormonal
Pharmacological treatment with Semaglutide (2.4 mg) achieves clinically relevant weight loss (~16%) regardless of the intensity of concurrent lifestyle interventions.
Take Semaglutide 2.4 mg once weekly. While you should still try to eat slightly less and move more, do not expect these lifestyle changes to drive your weight loss. The medication does the heavy lifting by correcting your biology. Expect ~16% weight loss over 68 weeks.
StrongSupportsHIGH confidence
The patients in STEP 1 and STEP 3 lost similar amounts of weight (~16%) with semaglutide 2.4 mg despite very different intensity in behaviour programs
Why this rating
Based on cited RCTs (STEP 1, STEP 3, STEP TEEN).
Source
The Concept of Healthy Behaviours in Obesity May Have Unintended Consequences
Hilary C. Craig et al. · Nutrients · 2022
narrative_reviewCited 4×
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