Hormonal
At higher doses (30% of energy), whey protein elicits a significantly greater insulinogenic response than soy protein, whereas at lower doses (15% of energy), both proteins produce similar insulin responses and have no differential effect on plasma glucose.
If you are healthy and normal weight, you can use either whey or soy protein for post-workout or meal supplementation without worrying about blood sugar spikes. At moderate amounts (around 15g protein), they behave the same. If you consume larger amounts (30g+), whey will trigger a higher insulin response than soy, but this did not negatively impact blood glucose levels in this study. For Asian Indians at higher risk for Type 2 Diabetes, moderate doses of either protein are equally effective for glucose homeostasis.
In conclusion, at higher doses, whey protein has a greater insulinogenic response, compared to soy protein, and exhibits a dose-response effect. However, at lower doses, whey and soy protein elicit similar insulinogenic responses, making them equally effective protein sources in relation to glucose homoeostasis.
Why this rating
Randomized, double-blind, crossover trial with adequate sample size (n=15) and rigorous statistical analysis (RMANOVA), though limited to healthy normal-weight Asian Indian males.
Source
The Effect of Soy and Whey Protein Supplementation on Glucose Homeostasis in Healthy Normal Weight Asian Indians
Sucharita Sambashivaiah et al. · Journal of Nutrition and Metabolism · 2023
DOI 10.1155/2023/2622057
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