Adherence
Multicomponent behavioral interventions, including Cognitive Behavioral Therapy (CBT) and Motivational Interviewing (MI), produce 5-10% weight loss and are essential for addressing psychological barriers and sustaining lifestyle changes.
Engage in structured behavioral programs that include self-monitoring, goal setting, and problem-solving. Cognitive Behavioral Therapy (CBT) is particularly effective for those with binge eating, while Motivational Interviewing (MI) helps resolve ambivalence. These interventions typically yield 5-10% weight loss and are most effective when combined with lifestyle changes and, if necessary, medication.
Multicomponent behavioral interventions—often including self-monitoring, dietary and physical activity counseling, and problem-solving—can produce 5–10% weight loss.
Why this rating
Supported by multiple studies and guidelines, though long-term maintenance remains challenging.
Source
Addressing the challenge of obesity in primary care: a review of effective interventions and implementation strategies
M Khani et al. · Diabetology & Metabolic Syndrome · 2025
DOI 10.1186/s13098-025-01925-z
More from this paper
- Anti-obesity medications (AOMs), particularly GLP-1 and dual GIP/GLP-1 agonists, produce significant weight loss (5-20%+) and should be continued long-term as disease-modifying agents rather than short-term aids.Good
- Combining aerobic and resistance exercise yields the best results for weight loss maintenance and metabolic health, with resistance training independently lowering obesity risk.Good
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
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