Research

Adherence

Mandibular advancement devices (MADs) provide symptom relief comparable to CPAP in mild-to-moderate OSA primarily due to superior long-term adherence, despite CPAP's superior objective efficacy in reducing AHI.

If you have mild-to-moderate sleep apnea and struggle with CPAP, ask about a mandibular advancement device. It might not reduce your apnea events as much as CPAP, but you are more likely to use it every night, which often leads to better overall health outcomes and symptom relief.

GoodQualifiesHIGH confidence
Mandibular advancement devices (MADs) consistently reduced AHI relative to placebo and produced symptom relief comparable to CPAP in mild-to-moderate OSA, largely due to superior adherence.
Jose Redondo et al. · Pathophysiology · 2026

Why this rating

Based on multiple RCTs and comparative cohorts cited in the review.

Source

Redefining Obstructive Sleep Apnea: Treatment in the Modern Era

Jose Redondo et al. · Pathophysiology · 2026

narrative_review
Read the paper

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →