Research
Hormonal
There are confirmed cases of falsified GLP-1 receptor agonists in Brazil, indicating supply chain vulnerabilities.
Counterfeit GLP-1 drugs have been confirmed in Brazil. Patients should obtain medications through regulated channels to avoid falsified products.
GoodSupportsHIGH confidence
Between January 2024 and September 2025, eight confirmed episodes of falsification were identified, involving seven cases of semaglutide and one case of liraglutide.
Why this rating
Confirmed regulatory alerts, though likely underestimates true volume.
Source
<scp>GLP</scp> ‐1 Receptor Agonists in Brazil: Landscape of Consumption, Safety and Regulation
Renato Lopes Hurtado et al. · Diabetes Obesity and Metabolism · 2026
DOI 10.1111/dom.70609
cross_sectional
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- GLP-1 receptor agonist consumption in Brazil is driven by socioeconomic capacity and access rather than epidemiological need, as evidenced by a significant positive correlation with GDP per capita and no correlation with obesity prevalence.Moderate
- Semaglutide is the predominant GLP-1 RA in Brazil, driving the majority of sales growth and adverse event reports, with significant off-label use for weight loss.Moderate
Related findings · Hormonal
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- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
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