Hormonal
Mutations in the preproghrelin/ghrelin gene are associated with obesity in humans, suggesting a genetic basis for energy balance regulation via the ghrelin pathway.
If you have a family history of obesity, it may be partly due to genetics affecting your hunger hormones (ghrelin). This doesn't mean you are doomed, but it does mean you might need to be more mindful of hunger cues and food environments than someone without this genetic risk. Consult a healthcare provider for personalized advice.
Mutations in the preproghrelin/ghrelin gene associated with obesity in humans
Why this rating
Published in The Journal of Clinical Endocrinology & Metabolism, a reputable peer-reviewed journal, but as a 'Rapid Communication' it may have limited sample size or follow-up compared to full studies.
Source
RAPID COMMUNICATIONS: Mutations in the Preproghrelin/Ghrelin Gene Associated with Obesity in Humans
Olavi Ukkola et al. · The Journal of Clinical Endocrinology & Metabolism · 2001
DOI 10.1210/jcem.86.8.7914
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