Research
Hormonal
Childhood adversities are associated with an increased risk of fatal or non-fatal CHD events in adulthood.
Early life trauma has long-lasting physical consequences, increasing the risk of heart disease later in life. While you cannot change your childhood, being aware of this risk factor allows for more proactive cardiovascular monitoring and stress management in adulthood.
GoodSupportsHIGH confidence
We further found that subjects with a high sum score of all 13 childhood experiences had a 10% increased hazard to develop fatal or non-fatal CHD events in adulthood (men: Exp (B)= 1.10 (1.05-1.15); P < 0.001 and women: (Exp (B)= 1.10 (1.02-1.19); P=0.011; Cox regression analysis adjusted for age).
Why this rating
Large cohort study with retrospective assessment of childhood adversities.
Source
Psychological stress, body shape and cardiovascular events: Results from the Whitehall II study
Britta Kubera et al. · Comprehensive Psychoneuroendocrinology · 2021
DOI 10.1016/j.cpnec.2021.100104
cohort · n=7107Cited 9×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Persistent psychological stress is causally associated with an increased risk of fatal or non-fatal coronary heart disease (CHD) events in a dose-dependent manner.Good
- High waist-to-hip ratio (WHR) is a significant predictor of all-cause mortality, whereas BMI is not, and psychological stress does not directly predict all-cause mortality when WHR is considered.Good
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