Research
Macro partitioning
A very-low-carbohydrate ketogenic diet (VLCKD) significantly improves triglycerides (TAG) and diastolic blood pressure (DBP) compared to a low-fat diet (LFD) over the long term, but also increases LDL-C and HDL-C levels.
Switching to a very-low-carb diet improves triglycerides and blood pressure more than a low-fat diet, but it will raise your LDL and HDL cholesterol. Discuss these changes with your doctor, as the increase in LDL may be less harmful than traditionally thought due to particle size changes.
GoodQualifiesHIGH confidence
Individuals assigned to a VLCKD showed decreased body weight... TAG... and diastolic blood pressure... while increased HDL-C... and LDL-C...
Why this rating
Meta-analysis of 13 RCTs.
Source
Very-low-carbohydrate ketogenic diet <i>v.</i> low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials
Nassib Bezerra Bueno et al. · British Journal Of Nutrition · 2013
DOI 10.1017/s0007114513000548
Meta-analysis · 13 studiesCited 771×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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