Research

Hormonal

Lorcaserin (10 mg once or twice daily) produces significant weight loss and improved glycemic control in patients with type 2 diabetes compared to placebo.

If you have Type 2 Diabetes and struggle with weight, lorcaserin (taken as a 10mg pill once or twice daily) can help you lose about 5% of your body weight over a year, which is significantly more than placebo. It also helps lower your blood sugar (HbA1c). This works best when combined with standard lifestyle changes like eating 600 calories less per day and exercising moderately for 30 minutes a day. Common side effects include nausea and headache, but severe low blood sugar was not observed in this study.

StrongSupportsHIGH confidence
Lorcaserin was associated with significant weight loss and improvement in glycemic control in patients with type 2 diabetes.
Patrick M. O’Neil et al. · Obesity · 2012

Why this rating

Randomized, double-blind, placebo-controlled clinical trial (RCT) with a large sample size (N=604).

Source

Randomized Placebo‐Controlled Clinical Trial of Lorcaserin for Weight Loss in Type 2 Diabetes Mellitus: The BLOOM‐DM Study

Patrick M. O’Neil et al. · Obesity · 2012

rct · n=604Cited 531×
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