Hormonal
Upon refeeding (cessation of ketosis) after significant weight loss (10-17%) on a ketogenic diet, hunger feelings and active ghrelin (AG) concentrations increase significantly, potentially undermining long-term weight maintenance.
When you stop the ketogenic diet and return to normal eating, expect your hunger and ghrelin levels to rise significantly. This is a physiological response to losing ketosis and weight. To mitigate this, transition gradually to your maintenance diet rather than stopping abruptly, and be aware that your body will signal for more food.
However, hunger feelings and AG concentrations increase significantly from baseline, once refeeding occurs.
Why this rating
Same study design as N1; strong within-subject comparison between ketotic and non-ketotic states.
Source
Timeline of changes in appetite during weight loss with a ketogenic diet
Siren Nymo et al. · International Journal of Obesity · 2017
DOI 10.1038/ijo.2017.96
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