Research
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C12TPP reduces food intake in mice, contributing to approximately one-third of the total body weight loss observed during treatment.
C12TPP treatment was associated with a significant decrease in food consumption, accounting for about 30% of the weight loss. This suggests the compound may influence appetite regulation pathways in addition to increasing metabolism.
ModerateSupportsMEDIUM confidence
Pair-feeding revealed that one-third of the body weight loss in C12TPP-treated mice was due to reduced food intake.
Why this rating
Supported by pair-feeding controls and direct measurement of food intake in mice.
Source
Mitochondria-targeted dodecyltriphenylphosphonium (C12TPP) combats high-fat-diet-induced obesity in mice
Anastasia Kalinovich et al. · International Journal of Obesity · 2016
DOI 10.1038/ijo.2016.146
mechanism_onlyCited 32×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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