Research
Hormonal
Intermittent fasting during Ramadan significantly reduces serum leptin levels in healthy young men, correlating with weight loss, while adiponectin levels remain largely unchanged.
Fasting for a month lowers your leptin levels, a hormone that signals energy stores to your brain. This drop correlates with your weight loss. Adiponectin, another metabolic hormone, stays relatively stable. This hormonal shift is part of the body's adaptation to reduced energy intake.
ModerateSupportsMEDIUM confidence
At the end-line phase, serum leptin had declined significantly, whereas serum adiponectin decreased by an insignificant amount compared with the level at baseline... Correlation coefficients show a significant correlation between the percentage change in body weight and percentage change in serum leptin concentration (r = 0.412; P = .037)
Why this rating
Single-arm observational study.
Source
Intermittent Fasting During Ramadan Improves Insulin Sensitivity and Anthropometric Parameters in Healthy Young Muslim Men
Guntari Prasetya et al. · American Journal of Lifestyle Medicine · 2018
DOI 10.1177/1559827618815430
crossover · n=27Cited 26×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Intermittent fasting during Ramadan significantly improves insulin sensitivity and reduces insulin resistance in healthy young men, independent of changes in fasting plasma glucose.Moderate
- Intermittent fasting during Ramadan leads to significant reductions in body weight, BMI, fat mass, and waist circumference in healthy young men, primarily driven by negative energy balance.Moderate
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