Research
Macro partitioning
Very Low-Calorie Ketogenic Diet (VLCKD) produces superior weight loss compared to low-carbohydrate diets and is recommended for severe obesity and specific metabolic conditions.
VLCKD is a very strict, low-calorie (<800 kcal) ketogenic diet that produces superior weight loss compared to standard low-carb diets. It is recommended for severe obesity and specific metabolic conditions under medical supervision. It is not suitable for everyone and has strict contraindications.
GoodSupportsHIGH confidence
VLCKD showed superior weight loss effect compared to low-carbohydrate diet... VLCKD is proposed as a dietary therapy method for obese patients.
Why this rating
Based on a clinical practice guideline citing European guidelines.
Source
Dietary Management of Obesity
Sang Hoon Lee et al. · Korean Journal of Gastroenterology · 2024
DOI 10.4166/kjg.2024.004
narrative_reviewCited 4×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- A daily caloric deficit of 500-1,000 kcal (low-calorie diet) produces a weight loss of 0.5-1.0 kg per week and up to 10% body weight over 6 months.Good
- Intermittent fasting (time-restricted feeding or alternate-day fasting) is not superior to continuous energy restriction for weight loss and may have limited long-term data.Moderate
Related findings · Macro partitioning
- Total daily protein intake of 1.6 g/kg/day is sufficient for maximizing resistance training-induced muscle gains, with an upper confidence interval of 2.2 g/kg/day.Strong
- Resistance exercise training combined with sufficient dietary protein intake acts synergistically to maximize skeletal muscle hypertrophy, with protein intake saturating around 1.6 g/kg/day for general populations and potentially requiring 2.0-2.2 g/kg/day for resistance-trained individuals.Strong
- Trans fats should be completely eliminated from the diet, as they increase LDL cholesterol, decrease HDL cholesterol, and are directly associated with increased coronary risk.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →