Research
Adherence
Higher adherence to the VLCKD program, measured by number of medical visits and total doses consumed, is positively associated with greater success in weight loss, BMI reduction, and fat mass loss.
Attend all scheduled medical and nutritional visits. The study shows that higher adherence, measured by attending visits and consuming the prescribed doses, is significantly associated with better weight loss and fat loss outcomes.
GoodSupportsHIGH confidence
baseline body weight and number of medical visits predict greater body weight loss success with highly significant p-values... High initial BMI and number of medical visits showed the greatest contributions to BMI reduction success
Why this rating
Large sample size and statistical significance, but observational nature limits causal inference regarding adherence.
Source
Phenotype-Driven Variability in Longitudinal Body Composition Changes After a Very Low-Calorie Ketogenic Intervention: A Machine Learning Cluster Approach
Víctor de la O et al. · Journal of Personalized Medicine · 2025
cohort · n=7775Cited 1×
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