Research
Adherence
Prolonged sedentary time is independently associated with increased risk for all-cause mortality, cardiovascular disease, cancer, and type 2 diabetes in adults, regardless of physical activity levels.
Reduce your total sitting time throughout the day. Even if you exercise regularly, prolonged sitting increases your risk for heart disease, diabetes, and early death. Break up long periods of sitting with standing or light movement.
GoodSupportsHIGH confidence
Prolonged sedentary time was independently associated with deleterious health outcomes regardless of physical activity.
Why this rating
Meta-analysis of 47 prospective cohort studies with large sample sizes, though heterogeneity and self-report bias are noted.
Source
Sedentary Time and Its Association With Risk for Disease Incidence, Mortality, and Hospitalization in Adults
Aviroop Biswas et al. · Annals of Internal Medicine · 2015
DOI 10.7326/m14-1651
Meta-analysis · 47 studiesCited 2,668×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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