Research
Hormonal
Adiponectin is an anti-inflammatory adipokine whose levels decrease in obesity, contrasting with most other adipokines that increase.
Maintaining healthy adiponectin levels, often associated with lower body fat and exercise, may help reduce inflammation and improve insulin sensitivity.
GoodSupportsHIGH confidence
Interestingly, adiponectin... appears to have an anti-inflammatory effect... in contrast to many other adipokines, its expression and release fall in obesity.
Why this rating
Cited studies (Arita, Hotta, Berg) consistently show this inverse relationship.
Source
Adipokines: inflammation and the pleiotropic role of white adipose tissue
Paul Trayhurn et al. · British Journal Of Nutrition · 2004
DOI 10.1079/bjn20041213
narrative_reviewCited 2,181×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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