Research

Adherence

Altered lifestyle interventions, specifically increased exercise and improved dietary habits, are more effective than pharmacological treatments for improving insulin sensitivity in patients with Nonalcoholic Steatohepatitis (NASH).

For individuals with fatty liver disease or NASH, focusing on lifestyle modifications—specifically increasing physical activity and improving dietary quality—is a primary strategy to improve insulin sensitivity. This approach is suggested to be potentially more effective than pharmacological attempts to correct insulin sensitivity alone. Patients should prioritize these behavioral changes as a core part of their management plan.

ModerateSupportsMEDIUM confidence
An altered lifestyle may be a more effective means of improving insulin sensitivity.
Brent A. Neuschwander‐Tetri et al. · Hepatology · 2003

Why this rating

The paper is a conference summary of pathogenesis and clinical aspects, citing observational data and animal models rather than a specific high-quality RCT for the lifestyle claim itself.

Source

Nonalcoholic Steatohepatitis: Summary of An Aasld Single Topic Conference

Brent A. Neuschwander‐Tetri et al. · Hepatology · 2003

DOI 10.1053/jhep.2003.50193

narrative_reviewCited 2,149×
Read the paper
DOI resolved against Crossref · corpus check 2026-06-10

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →