Hormonal

In the pathogenesis of type 2 diabetes, defects in both insulin action (resistance) and insulin secretion (dysfunction) occur early during the transition from normal glucose tolerance to impaired glucose tolerance, and both must be targeted for effective intervention.

If you are at risk for type 2 diabetes (e.g., prediabetes), focusing solely on one aspect of metabolic health is likely insufficient. You must address both how your body uses insulin (resistance) and how well your pancreas produces it (secretion). This typically involves lifestyle interventions that improve sensitivity (like exercise and weight management) while also supporting pancreatic function (often through weight loss and reducing metabolic stress). Early intervention is critical because these defects worsen over time.