Hormonal
Weight loss of 4–10 kg in obese subjects significantly reduces LDL-C by approximately 12% and increases LDL receptor mRNA levels by 27%.
Losing 4 to 10 kg of body weight can significantly improve your cholesterol profile, specifically lowering LDL-C by about 12%. This is achieved through a combination of calorie restriction and exercise, which improves your body's ability to clear LDL from the blood by increasing LDL receptor activity.
A weight loss of 4–10 kg in obese subjects resulted in a 12% reduction in LDL-C and a 27% increase in LDL receptor mRNA levels [111,115].
Why this rating
The paper cites specific studies ([111,115]) showing quantitative changes, though it is a review paper summarizing these findings rather than presenting primary trial data itself.
Source
Dyslipidemia in Obesity: Mechanisms and Potential Targets
Boudewijn Klop et al. · Nutrients · 2013
DOI 10.3390/nu5041218
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