Research

Mixed

High levels of leisure-time physical activity (90th percentile vs 10th) are associated with a significantly lower risk of 13 specific cancer types, including esophageal adenocarcinoma, liver, lung, kidney, gastric cardia, endometrial, myeloid leukemia, myeloma, colon, head and neck, rectal, bladder, and breast cancer.

Engaging in high levels of leisure-time physical activity (moderate to vigorous intensity, such as brisk walking or running) is strongly associated with a reduced risk of developing 13 common types of cancer, including breast, colon, lung, and kidney cancer. This benefit exists independently of weight loss for most cancers, meaning you should prioritize consistent physical activity for cancer prevention regardless of your current body weight.

StrongSupportsVERY_HIGH confidence
High vs low levels of leisure-time physical activity were associated with lower risks of 13 cancers: esophageal adenocarcinoma (HR 0.58...), liver (HR 0.73...), lung (HR 0.74...), kidney (HR 0.77...), gastric cardia (HR 0.78...), endometrial (HR 0.79...), myeloid leukemia (HR 0.80...), myeloma (HR 0.83...), colon (HR 0.84...), head and neck (HR 0.85...), rectal (HR 0.87...), bladder (HR 0.87...), and breast (HR 0.90...).
Steven C. Moore et al. · JAMA Internal Medicine · 2016

Why this rating

Large-scale pooled analysis of 1.44 million participants across 12 prospective cohorts with rigorous statistical controls.

Source

Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults

Steven C. Moore et al. · JAMA Internal Medicine · 2016

cohort · n=1440000Cited 1,482×
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