Adherence
High levels of leisure-time physical activity are associated with an increased risk of malignant melanoma and non-advanced prostate cancer.
While physical activity reduces the risk of most cancers, it is associated with a slightly higher risk of melanoma and prostate cancer. For melanoma, this is likely due to outdoor sun exposure; use sun protection when exercising outdoors. For prostate cancer, the increased risk is likely due to higher screening rates in active men, leading to the diagnosis of slow-growing cancers that may not have caused symptoms. Continue exercising, but ensure appropriate sun safety and regular age-appropriate cancer screenings.
Leisure-time physical activity was associated with higher risks of malignant melanoma (HR 1.27, 95% CI 1.16-1.40) and prostate cancer (HR 1.05, 95% CI 1.03-1.08).
Why this rating
Large sample size, but the mechanisms are behavioral (UV exposure, screening bias) rather than direct physiological protection.
Source
Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults
Steven C. Moore et al. · JAMA Internal Medicine · 2016
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