Adherence
High levels of leisure-time physical activity are associated with an increased risk of malignant melanoma and non-advanced prostate cancer.
While physical activity reduces the risk of most cancers, it is associated with a slightly higher risk of melanoma and prostate cancer. For melanoma, this is likely due to outdoor sun exposure; use sun protection when exercising outdoors. For prostate cancer, the increased risk is likely due to higher screening rates in active men, leading to the diagnosis of slow-growing cancers that may not have caused symptoms. Continue exercising, but ensure appropriate sun safety and regular age-appropriate cancer screenings.
Leisure-time physical activity was associated with higher risks of malignant melanoma (HR 1.27, 95% CI 1.16-1.40) and prostate cancer (HR 1.05, 95% CI 1.03-1.08).
Why this rating
Large sample size, but the mechanisms are behavioral (UV exposure, screening bias) rather than direct physiological protection.
Source
Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults
Steven C. Moore et al. · JAMA Internal Medicine · 2016
DOI 10.1001/jamainternmed.2016.1548
Related findings · Adherence
- Regular physical activity (at least 150 minutes/week of moderate-intensity) reduces all-cause and cardiovascular mortality by 20-30% and lowers the risk of type 2 diabetes by 25-35%.Strong
- Increasing physical activity from a sedentary lifestyle to an active one in middle adulthood significantly reduces the risk of coronary events compared to remaining sedentary.Strong
- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →