Research
Hormonal
Higher sodium intake is associated with an increased risk of stroke, stroke mortality, and coronary heart disease mortality in adults.
While direct mortality data from trials is limited, observational evidence suggests that high sodium intake increases the risk of stroke and heart disease death. Maintaining moderate sodium levels supports long-term cardiovascular health.
ModerateSupportsMEDIUM confidence
Increased sodium intake was associated with an increased risk of stroke (risk ratio 1.24, 95% confidence interval 1.08 to 1.43), stroke mortality (1.63, 1.27 to 2.10), and coronary heart disease mortality (1.32, 1.13 to 1.53).
Why this rating
Evidence is derived from cohort studies, which are rated 'low' or 'very low' quality by GRADE due to observational design, though the association is statistically significant.
Source
Effect of lower sodium intake on health: systematic review and meta-analyses
Nancy Aburto et al. · BMJ · 2013
DOI 10.1136/bmj.f1326
Meta-analysis · 64 studiesCited 1,245×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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