Research
Hormonal
SGLT2 inhibitors are recommended for type 2 diabetes patients with chronic kidney disease (CKD) to prevent CKD progression, heart failure hospitalization, MACE, and cardiovascular death.
If you have type 2 diabetes and chronic kidney disease, ask your doctor about SGLT2 inhibitors. These drugs are proven to slow the progression of kidney disease and reduce the risk of heart failure and cardiovascular death, offering protection beyond blood sugar control.
WeakSupportsHIGH confidence
SGLT2 inhibitors are recommended to prevent the progression of CKD, hHF, MACE, and CV death in patients with type 2 diabetes with CKD.
Why this rating
Based on CREDENCE and other CVOTs.
Source
2019 Update to: Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
John B. Buse et al. · Diabetes Care · 2019
DOI 10.2337/dci19-0066
clinical_guidelineCited 1,186×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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