Research

Macro partitioning

A low-fat dietary intervention significantly reduces LDL cholesterol, diastolic blood pressure, and Factor VIIc levels, but does not significantly affect HDL cholesterol, triglycerides, glucose, or insulin levels.

If you follow a low-fat diet, you can expect a modest drop in LDL cholesterol and blood pressure. However, do not expect significant improvements in HDL cholesterol, triglycerides, or blood sugar control from this dietary pattern alone.

StrongQualifiesHIGH confidence
Low-density lipoprotein cholesterol levels, diastolic blood pressure, and factor VIIc levels were significantly reduced by 3.55 mg/dL, 0.31 mm Hg, and 4.29%, respectively; levels of high-density lipoprotein cholesterol, triglycerides, glucose, and insulin did not significantly differ in the intervention vs comparison groups.
Barbara V. Howard et al. · JAMA · 2006

Why this rating

Derived from the same high-quality RCT with a subsample of biomarkers.

Source

Low-Fat Dietary Pattern and Risk of Cardiovascular Disease

Barbara V. Howard et al. · JAMA · 2006

rct · n=48835Cited 1,089×
Read the paper

This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →