Research
Macro partitioning
Dietary patterns rich in whole grains, vegetables, fruits, and fish are associated with lower circulating concentrations of inflammatory markers, while saturated fats, trans fats, and high glycemic loads promote inflammation.
To reduce inflammation, prioritize whole grains, vegetables, fruits, and fish. Limit saturated and trans fats, and manage carbohydrate quality to avoid high glycemic spikes. This dietary pattern directly lowers inflammatory markers associated with obesity and metabolic disease.
GoodSupportsHIGH confidence
Healthy eating patterns are associated with lower circulating concentrations of inflammatory markers. Among the components of a healthy diet, whole grains, vegetables and fruits, and fish are all associated with lower inflammation. SFA and trans-MUFA are pro-inflammatory, while PUFA, especially long-chain n-3 PUFA, are anti-inflammatory. Hyperglycaemia induces both postprandial and chronic low-grade inflammation.
Why this rating
Based on a comprehensive review of dietary components and their effects on inflammation markers.
Source
Dietary factors and low-grade inflammation in relation to overweight and obesity
Philip C. Calder et al. · British Journal Of Nutrition · 2011
DOI 10.1017/s0007114511005460
narrative_reviewCited 1,068×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Obesity is characterized by systemic chronic low-grade inflammation driven by adipose tissue-derived mediators (adipokines) and infiltrating immune cells, which contributes to insulin resistance and metabolic complications.Good
- Postprandial inflammation occurs after meals, particularly those high in glucose or fat, and is exaggerated in obese and diabetic individuals, but can be mitigated by antioxidants and specific dietary components.Good
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