Research
Adherence
Prolonged sitting time is associated with a 30% higher risk of endometrial cancer and a 30% higher risk of colorectal cancer, independent of moderate-to-vigorous physical activity.
Try to minimize prolonged sitting throughout the day. Even if you exercise regularly, breaking up sitting time can further lower your risk of endometrial and colorectal cancers.
GoodSupportsMEDIUM confidence
Meta-analyses (84,85) consistently have shown prolonged sitting time is associated with an approximate 30% higher risk of endometrial cancer after adjustment for moderate-to-vigorous physical activity, and the recent meta-analysis by Lynch et al... reported 36% higher risk of endometrial cancer... Similarly, prolonged sitting time has been associated with a 30% higher risk of colorectal cancer
Why this rating
Consistent meta-analyses, but heterogeneity exists.
Source
American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control
Alpa V. Patel et al. · Medicine & Science in Sports & Exercise · 2019
DOI 10.1249/mss.0000000000002117
narrative_reviewCited 849×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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