Hormonal

Increased body mass index (BMI) is strongly associated with a higher risk of developing oesophageal adenocarcinoma, colon and rectal cancer in men, biliary tract system cancer, pancreatic cancer, endometrial cancer (premenopausal), kidney cancer, and multiple myeloma.

Maintaining a healthy body weight is a critical, evidence-based strategy for reducing the risk of several major cancers, including colorectal, pancreatic, kidney, and endometrial cancers. This is not just about aesthetics; it is a direct modifiable risk factor. For men, colorectal risk is particularly sensitive to BMI increases. For women, maintaining a healthy weight, especially before menopause, is crucial for endometrial health. Public health guidelines should target these populations for personalized prevention strategies.