Macro partitioning
High carbohydrate intake is positively associated with the abundance of the archaeal genus Methanobrevibacter and the fungal genus Candida in the human gut microbiome, whereas high protein, amino acid, and fatty acid intake is negatively associated with these taxa.
If you eat a diet high in carbohydrates, you are likely to have higher levels of Methanobrevibacter (an archaea) and Candida (a fungus) in your gut. Conversely, diets high in protein, amino acids, and fats are associated with lower levels of these specific taxa. This relationship holds for both long-term dietary habits and recent food intake, particularly for Candida.
Methanobrevibacter and Candida were positively associated with diets high in carbohydrates, but negatively with diets high in amino acids, protein, and fatty acids.
Why this rating
Large cohort (n=96), deep sequencing, and rigorous statistical controls (Permanova, FDR), though observational nature limits causal inference.
Source
Archaea and Fungi of the Human Gut Microbiome: Correlations with Diet and Bacterial Residents
Christian Hoffmann et al. · PLoS ONE · 2013
DOI 10.1371/journal.pone.0066019
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