Research
Adherence
Stress management and nutritional supplements (Calcium, Magnesium, Potassium, Fish Oil) do not significantly lower blood pressure in individuals with high-normal diastolic blood pressure.
For people with high-normal blood pressure, stress management and common nutritional supplements (Calcium, Magnesium, Potassium, Fish Oil) are not effective strategies for lowering blood pressure, even when taken as directed. Focus on weight loss and sodium reduction instead.
StrongRefutesHIGH confidence
Despite good compliance, neither stress management nor nutritional supplements reduced diastolic blood pressure or systolic blood pressure significantly (P>.05).
Why this rating
Randomized control multicenter trial with high compliance and blinded outcome measurement.
Source
The Effects of Nonpharmacologic Interventions on Blood Pressure of Persons With High Normal Levels
Paul K. Whelton · JAMA · 1992
DOI 10.1001/jama.1992.03480090061028
rct · n=2182Cited 746×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
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- Weight reduction significantly lowers blood pressure in individuals with high-normal diastolic blood pressure, producing a net reduction of 2.3 mm Hg in diastolic and 2.9 mm Hg in systolic pressure over 18 months.Strong
- Sodium reduction significantly lowers blood pressure in individuals with high-normal diastolic blood pressure, producing a net reduction of 0.9 mm Hg in diastolic and 1.7 mm Hg in systolic pressure over 18 months.Strong
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