Hormonal
Vitamin D supplementation (≥792 IU/day) significantly reduces the risk of hip fractures (by 30%) and non-vertebral fractures (by 14%) in adults, particularly when combined with calcium.
To reduce fracture risk, aim for 800 IU of Vitamin D3 daily, ideally combined with 1200mg of Calcium. This combination has been shown in large studies to significantly lower hip and non-vertebral fracture rates. Ensure you are actually taking the supplement consistently, as poor adherence negates benefits.
A meta-analysis of more than 30,000 participants did show that supplementation with vitamin D (≥792 IU/day) led to a significant reduction in the risk of fracture; the risk of hip fracture was reduced by 30%, the risk of any non-vertebral fracture by 14% [98–106].
Why this rating
Based on a large meta-analysis (>30,000 participants) and specific RCTs, though some individual studies (RECORD) showed no benefit due to compliance/monitoring issues.
Source
Vitamin D — Effects on Skeletal and Extraskeletal Health and the Need for Supplementation
Matthias G. Wacker et al. · Nutrients · 2013
DOI 10.3390/nu5010111
More from this paper
- Vitamin D supplementation (700–1000 IU/day) reduces the risk of falls by 19-23% in adults, but only when serum 25(OH)D levels reach at least 24 ng/mL.Good
- Vitamin D supplementation (1100 IU/day) combined with Calcium (1400-1500 mg/day) reduces the relative risk of cancer incidence by ~60% in postmenopausal women.Moderate
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