Research
Hormonal
Statins are effective for primary and secondary prevention of cardiovascular disease in patients with diabetes, providing significant risk reduction even in patients with low baseline LDL cholesterol.
If you have diabetes, you should likely be on a statin, even if your cholesterol numbers look okay. Statins significantly reduce your risk of heart attack and stroke, and this benefit exists regardless of your baseline LDL. The small risk of developing diabetes from statins is far outweighed by the protection they offer your heart. Discuss high-intensity statins with your doctor if you are over 40 or have other risk factors.
StrongSupportsVERY_HIGH confidence
There is a wealth of clinical trial evidence that lowering serum cholesterol with statins decreases the risk of CHD... It would appear from such trials that the relative risk reduction achieved with statin treatment is similar in patients with diabetes to that in other people.
Why this rating
Backed by multiple large RCTs (CARDS, HPS, 4S, etc.) and meta-analyses.
Source
Diabetes Dyslipidemia
Jonathan Schofield et al. · Diabetes Therapy · 2016
narrative_reviewCited 405×
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