Research
Adherence
Weight loss through lifestyle modification in obese women restores menstrual cyclicity and ovulation, thereby improving the likelihood of conception.
Lose weight through diet and exercise. This is not just for health but specifically to restore ovulation and improve your chances of getting pregnant. The paper states this is proven to work.
GoodSupportsHIGH confidence
On the contrary, weight loss programs through lifestyle modification in obese women, have been proven to restore menstrual cyclicity and ovulation and improve the likelihood of conception.
Why this rating
Cited as 'proven' in the abstract, supported by general review of lifestyle impacts.
Source
Obesity as disruptor of the female fertility
Erica Silvestris et al. · Reproductive Biology and Endocrinology · 2018
DOI 10.1186/s12958-018-0336-z
narrative_reviewCited 652×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Obesity disrupts female fertility through multiple mechanisms including HPO axis deregulation, adipokine-mediated inflammation, and oocyte quality reduction, leading to anovulation and reduced IVF success rates.Good
- Adipokines (leptin, adiponectin, resistin, etc.) released by adipose tissue in obesity directly interfere with ovarian function, insulin sensitivity, and endometrial receptivity, contributing to infertility.Good
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- Resistance exercise is the only intervention capable of consistently restoring muscle function and strength in sarcopenia, partially overcoming age-related anabolic resistance.Strong
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