Research

Macro partitioning

Short-term consumption of low-carbohydrate, high-protein weight-loss diets reduces the abundance of butyrate-producing bacteria (e.g., Roseburia, Eubacterium rectale) and lowers total SCFA levels, particularly butyrate.

If following a low-carb diet for weight loss, be aware that it may reduce beneficial butyrate-producing bacteria and SCFA levels. Consider incorporating low-FODMAP fermentable fibers if tolerated, or monitor for long-term gut health implications, as long-term adherence may increase colonic disease risk.

GoodSupportsHIGH confidence
With a reduction in dietary carbohydrate intake, there was also a corresponding decrease in the abundance of Roseburia spp. and Eubacterium rectale... Total SCFA were also reduced in response to lowering carbohydrate intake... with a disproportionate decrease in faecal butyrate...
Hannah L. Simpson et al. · Alimentary Pharmacology & Therapeutics · 2015

Why this rating

Based on controlled crossover studies (Duncan et al., Brinkworth et al.) with clear mechanistic links between substrate availability and bacterial abundance.

Source

Review article: dietary fibre-microbiota interactions

Hannah L. Simpson et al. · Alimentary Pharmacology & Therapeutics · 2015

narrative_reviewCited 611×
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