Hormonal
Serum estrone (E1) and estradiol (E2) are positively associated with bone mineral density (BMD) in elderly men, independent of testosterone levels.
Elderly men should understand that estrogen (derived from testosterone) is vital for bone health. Low estrogen levels, even if testosterone is normal, can contribute to bone loss. Monitoring bioavailable estrogen may be as important as testosterone for preventing osteoporosis in aging men.
E1 and E2 were both positively, independently associated with BMD... The positive relation between T and BMD was independent of E2.
Why this rating
Cross-sectional observational study; associations are significant but causality is precluded by study design.
Source
Measures of Bioavailable Serum Testosterone and Estradiol and Their Relationships with Muscle Strength, Bone Density, and Body Composition in Elderly Men*
Annewieke W. van den Beld et al. · The Journal of Clinical Endocrinology & Metabolism · 2000
DOI 10.1210/jcem.85.9.6825
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