Hormonal
Restricting sleep to 5 hours per night for one week significantly reduces insulin sensitivity in healthy men, as measured by both intravenous glucose tolerance tests and euglycemic-hyperinsulinemic clamps.
If you are a healthy adult, restricting your sleep to 5 hours a night for just one week can significantly reduce your body's ability to handle glucose (insulin sensitivity). This happens even if you feel alert (especially if taking stimulants like modafinil). To maintain metabolic health, prioritize getting adequate sleep (7+ hours) rather than sacrificing it for extra waking hours.
Sleep restriction (5 h/night) for 1 week significantly reduces insulin sensitivity, raising concerns about effects of chronic insufficient sleep on disease processes associated with insulin resistance.
Why this rating
Randomized, double-blind, placebo-controlled, crossover design in healthy men with gold-standard metabolic measurements (clamp), though limited to a specific demographic.
Source
Sleep Restriction for 1 Week Reduces Insulin Sensitivity in Healthy Men
Orfeu M. Buxton et al. · Diabetes · 2010
DOI 10.2337/db09-0699
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