Hormonal
Type 2 diabetes negates the natural cardiovascular protection typically afforded to premenopausal women, resulting in a 25–50% greater excess risk of incident cardiovascular disease in women compared to men with diabetes.
If you have type 2 diabetes, your risk of heart disease is not lower than a man's, even if you are a woman. Diabetes removes the natural heart protection women usually have. You need to manage blood pressure, lipids, and blood sugar as aggressively as a man would to protect your heart.
Large-scale observational studies suggest that type 2 diabetes confers 25–50% greater excess risk of incident CVD in women compared with men.
Why this rating
Based on large-scale meta-analyses and cohort studies (e.g., UK Biobank, QRISK3), though some contemporary studies show inconsistent results.
Source
Sex differences in the burden of type 2 diabetes and cardiovascular risk across the life course
Amy G. Huebschmann et al. · Diabetologia · 2019
DOI 10.1007/s00125-019-4939-5
More from this paper
- Females have higher rates of insulin resistance than males from early childhood through mid-puberty, whereas males exhibit greater insulin resistance during late puberty and adulthood.Good
- Women with type 2 diabetes are undertreated for cardiovascular risk factors (HbA1c, blood pressure, lipids) compared to men, contributing to worse outcomes.Good
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