Hormonal
Short-term intensive insulin therapy improves beta-cell function and insulin sensitivity, increasing the likelihood of achieving type 2 diabetes remission compared to oral hypoglycemic agents alone.
For early-stage Type 2 Diabetes, short-term intensive insulin therapy can help restore your pancreas's ability to produce insulin. This approach is more effective for achieving remission than oral medications alone, though it requires strict adherence and monitoring during the intensive phase.
Short-term intensive insulin therapy can improve beta-cell function, increase insulin sensitivity, and reduce hepatic insulin resistance, increasing the chances of achieving T2D remission weeks or months after treatment is ceased compared to treatment with oral hypoglycemic agents alone.
Why this rating
Based on a systematic mapping of registered trials citing previous meta-analyses, but the paper itself is a mapping study, not a primary clinical trial.
Source
Registered clinical trials targeting type 2 diabetes remission with pharmacological interventions
Nicholas Shoung et al. · Scientific Reports · 2025
DOI 10.1038/s41598-025-00080-9
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