Macro partitioning
An isocaloric Mediterranean diet intervention significantly lowers total, LDL, and HDL plasma cholesterol in overweight and obese adults within 4 weeks, independent of energy intake or physical activity changes.
If you are overweight or obese, switching to a Mediterranean dietary pattern can lower your total and LDL cholesterol within just 4 weeks, even if you do not lose weight or change your exercise habits. Focus on replacing meat and refined cereals with fruits, vegetables, whole grains, legumes, and nuts. The greater your adherence to this pattern, the more your cholesterol drops.
An isocaloric 8- week intervention with an MD in obese and overweight subjects leads to a decrease in total, low- density lipoprotein and high- density lipoprotein plasma cholesterol and faecal bile acids levels independently of energy intake, the decrease in cholesterol being proportional to MD adherence rates.
Why this rating
Randomized controlled trial (RCT) with 82 participants, isocaloric design, and objective biomarker measurements.
Source
Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake
Victoria Meslier et al. · Gut · 2020
DOI 10.1136/gutjnl-2019-320438
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