Hormonal
Chronic intake of decaffeinated green tea extracts (455 mg catechins/day) reduces atherosclerotic factors (TNF-α, sICAM-1, MCP-1, CRP) in hemodialysis patients.
For individuals with kidney issues requiring dialysis, decaffeinated green tea extract (455mg catechins daily) has been shown in studies to lower inflammatory markers associated with heart disease. This suggests a targeted supplement strategy for this specific high-risk group, distinct from general population advice.
In hemodialysis patients, the chronic administration (3th and 5th month of a seven month study) of decaffeinated green tea extracts (catechins tablet; 455 mg/d comparable to four cups of green tea) decreased atherosclerotic factors such as tumor necrosis factor (TNF-α), soluble intercellular adhesion molecule 1 (sICAM-1), monocyte chemoattractant protein 1 (MCP-1), and C reactive protein (CRP) with respect to the control group receiving placebo...
Why this rating
Cites a specific clinical study in a niche population; the paper notes general controversy in bioavailability but accepts this specific finding.
Source
Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence
Sonia de Pascual‐Teresa et al. · International Journal of Molecular Sciences · 2010
DOI 10.3390/ijms11041679
More from this paper
- Consumption of flavanol-rich cocoa (approx. 821 mg flavanols/day) induces vasodilation via nitric oxide (NO) system activation, providing a mechanism for protection against coronary events.Moderate
- High intake of flavonols and flavan-3-ols is associated with a reduced relative risk of ischaemic stroke (0.55 and 0.59 respectively) and potentially reduced CVD mortality in middle-aged men.Moderate
Related findings · Hormonal
- Initial treatment for type 2 diabetes should be a combination of metformin and either an SGLT-2 inhibitor or a GLP-1 receptor agonist to achieve cardiorenal protection, rather than monotherapy or older agents like sulfonylureas.Strong
- For patients with specific monogenic obesity syndromes (leptin deficiency, POMC/PCSK1/LEPR mutations), targeted pharmacotherapy (recombinant leptin or setmelanotide) is highly effective and should be prioritized, unlike in polygenic obesity.Strong
- Continued weekly administration of 2.4 mg subcutaneous semaglutide prevents weight regain and promotes further weight loss in adults with overweight or obesity, whereas switching to placebo results in significant weight regain.Strong
This is one finding among thousands. Every one is graded and traced to its source, so you can see what the evidence actually supports. Browse the research →