Research
Hormonal
High caffeine consumption (>500 mg/day) is associated with reduced fecundity and delayed conception, although the evidence is considered equivocal.
If you are trying to conceive, consider limiting your caffeine intake to less than 500 mg per day (about 4-5 cups of coffee). While the evidence is not definitive, reducing caffeine may improve your chances of conception.
ModerateQualifiesMEDIUM confidence
The consumption of caffeine has been associated with reduced fecundity in the general population... A large multicentred study from five European countries found an increased risk of subfecundity for women consuming large amounts (>500 mg) of caffeine per day
Why this rating
Studies show association but lack consensus and consistency.
Source
The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review
Gillian Homan et al. · Human Reproduction Update · 2007
DOI 10.1093/humupd/dml056
narrative_reviewCited 549×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
More from this paper
- Female age is a primary determinant of reproductive performance, with a significant decline in fertility starting in the mid-to-late 20s and a steep drop after age 35, affecting both natural conception and ART success rates.Strong
- Smoking (active and passive) significantly reduces fertility in both men and women, delaying conception and reducing ART success rates, with mechanisms including DNA damage, altered hormone levels, and zona pellucida thickening.Strong
- Maintaining a healthy body weight (BMI 20-25) is crucial for fertility, as both obesity (BMI >30) and underweight (BMI <20) are associated with delayed conception, ovulatory dysfunction, and reduced ART success rates.Strong
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