Hormonal
Circulating miR-19a/b and miR-125b are associated with features of metabolic syndrome and cardiovascular disease risk, including biomarkers of atherosclerosis.
Elevated levels of miR-19a/b and miR-125b in the blood may signal an increased risk of cardiovascular issues and metabolic dysfunction in people with fatty liver. This suggests that liver health is closely tied to heart health, and monitoring these markers could help assess overall metabolic risk.
Circulating miR-19a/b and miR-125b were correlated with biomarkers of atherosclerosis.
Why this rating
Validated in an independent replication set with significant associations to clinical parameters.
Source
Circulating microRNA signature in non-alcoholic fatty liver disease: from serum non-coding RNAs to liver histology and disease pathogenesis
Carlos J. Pirola et al. · Gut · 2014
DOI 10.1136/gutjnl-2014-306996
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