Macro partitioning
Higher intake of polyunsaturated fat is associated with a significantly lower risk of coronary heart disease (CHD) in women, particularly among those younger than 65 years or with a BMI ≥ 25 kg/m².
Focus on the type of fat you eat rather than just cutting total fat. Increasing your intake of polyunsaturated fats (like those in vegetable oils, nuts, and fish) is linked to a lower risk of heart disease, especially if you are under 65 or overweight. Conversely, avoid trans fats, which increase risk.
Polyunsaturated fat intake was inversely associated with CHD risk (multivariate relative risk (RR) for the highest vs. the lowest quintile = 0.75, 95% confidence interval (CI): 0.60, 0.92; ptrend = 0.004)... The inverse association between polyunsaturated fat intake and CHD risk was strongest among women whose body mass index was ≥ 25 kg/m².
Why this rating
Large prospective cohort (78,778 women), long follow-up (20 years), repeated dietary assessments, and rigorous multivariate adjustment.
Source
Dietary Fat Intake and Risk of Coronary Heart Disease in Women: 20 Years of Follow-up of the Nurses' Health Study
Kyungwon Oh · American Journal of Epidemiology · 2005
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