Research
Macro partitioning
Higher intake of trans-fat is associated with a significantly increased risk of coronary heart disease (CHD) in women, particularly among those younger than 65 years.
Minimize your intake of trans-fats, as they are linked to a higher risk of heart disease. This risk is particularly pronounced in younger women and those with a lower body weight. Focus on replacing trans-fats with healthier fats like polyunsaturated fats.
GoodRefutesHIGH confidence
Trans-fat intake was associated with an elevated risk of CHD (RR = 1.33, 95% CI: 1.07, 1.66; ptrend = 0.01)... trans-fat intake was most strongly related to risk of CHD among women younger than age 65 years (RR = 1.50, 95% CI: 1.13, 2.00; ptrend = 0.01)
Why this rating
Large prospective cohort, long follow-up, repeated dietary assessments, and rigorous multivariate adjustment.
Source
Dietary Fat Intake and Risk of Coronary Heart Disease in Women: 20 Years of Follow-up of the Nurses' Health Study
Kyungwon Oh · American Journal of Epidemiology · 2005
DOI 10.1093/aje/kwi085
cohort · n=78778Cited 498×
Read the paper DOI resolved against Crossref · corpus check 2026-06-10
Related findings · Macro partitioning
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