Hormonal
Oral semaglutide significantly improves glycemic control (HbA1c reduction) and promotes weight loss in patients with type 2 diabetes compared to placebo, with efficacy scaling with dosage up to 40mg.
If you have Type 2 Diabetes and struggle with blood sugar or weight, oral semaglutide is a proven, once-daily pill option that works significantly better than a placebo for lowering HbA1c and reducing weight. It is titrated up slowly to minimize stomach upset, which is a common but usually manageable side effect. It is not a substitute for diet and exercise but works alongside them.
Among patients with type 2 diabetes, oral semaglutide resulted in better glycemic control than placebo over 26 weeks... Reductions in body weight were greater with oral semaglutide... vs placebo... and significant for oral semaglutide dosages of 10 mg or more vs placebo
Why this rating
Randomized, double-blind, placebo-controlled clinical trial with 632 participants.
Source
Effect of Oral Semaglutide Compared With Placebo and Subcutaneous Semaglutide on Glycemic Control in Patients With Type 2 Diabetes
Melanie J. Davies et al. · JAMA · 2017
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