Research

Mixed

Lifestyle interventions combining dietary changes and physical activity significantly reduce the risk of developing type 2 diabetes in high-risk individuals (those with impaired glucose tolerance or metabolic syndrome).

If you have impaired glucose tolerance or metabolic syndrome, combining modest weight loss (5-7% of body weight) with increased physical activity (aiming for ~150 minutes per week) and a diet lower in saturated fat and higher in fiber can reduce your risk of developing type 2 diabetes by nearly half. These benefits can last for many years, even after the active intervention ends.

StrongSupportsVERY_HIGH confidence
In seven trials involving 4090 participants [32–34,36–38,40], lifestyle intervention significantly decreased T2D risk compared to control groups (RR = 0.53 (95% CI: 0.41, 0.67), p < 0.001)... We conclude that T2D is preventable by changing lifestyle and the risk reduction is sustained for many years after the active intervention (high certainty of evidence).
Matti Uusitupa et al. · Nutrients · 2019

Why this rating

The study used a systematic review and meta-analysis of 7 RCTs with 4090 participants, graded as 'HIGH' certainty by GRADE.

Source

Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis

Matti Uusitupa et al. · Nutrients · 2019

Meta-analysis · 7 studiesCited 467×
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